In the year 1954, US Marshall Teddy Daniels (Leonardo DiCaprio) and his new partner Chuck Aule (Mark Ruffalo) are assigned to investigate a patient running away from prisoner hospital. The hospital is for crazy criminals. It has super security and placed on Shutter Island. Once he arrives at the island, the two marshals get difficulty in their investigation. It is because the staff of the hospital won’t cooperate to them. They do not get any useful information from them. But Teddy still believes that he can find the lost patient and solve the mystery and the weird thing he found in the island.